2024

Covert, Lauren T., Alaa Osman, and George A. Truskey. “Interferon-β-Induced Injury During Pediatric Muscle Differentiation: Insight Into Juvenile Dermatomyositis Pathogenesis.” ACR Open Rheumatol, October 22, 2024. https://doi.org/10.1002/acr2.11760.

Vakili, Sahar, Elizabeth K. Izydore, Leonhard Losert, Wayne A. Cabral, Urraca L. Tavarez, Kevin Shores, Huijing Xue, et al. “Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature.” Aging Cell, October 2024, e14375. https://doi.org/10.1111/acel.14375.

Covert, Lauren T., Joseph A. Prinz, Devjanee Swain-Lenz, Jeffrey Dvergsten, and George A. Truskey. “Genetic changes from type I interferons and JAK inhibitors: clues to drivers of juvenile dermatomyositis.” Rheumatology (Oxford) 63, no. SI2 (September 1, 2024): SI240–48. https://doi.org/10.1093/rheumatology/keae082.

Lopez, Isabella, and George A. Truskey. “Multi-cellular engineered living systems to assess reproductive toxicology.” Reproductive Toxicology (Elmsford, N.Y.) 127 (August 2024): 108609. https://doi.org/10.1016/j.reprotox.2024.108609.

Khodabukus, Alastair, Neel K. Prabhu, Taylor Roberts, Meghan Buldo, Amber Detwiler, Zachary D. Fralish, Megan E. Kondash, George A. Truskey, Timothy R. Koves, and Nenad Bursac. “Bioengineered Model of Human LGMD2B Skeletal Muscle Reveals Roles of Intracellular Calcium Overload in Contractile and Metabolic Dysfunction in Dysferlinopathy.” Adv Sci (Weinh) 11, no. 31 (August 2024): e2400188. https://doi.org/10.1002/advs.202400188.

Mishra, Saurabh, Nicole Welch, Shashi Shekhar Singh, Khuraijam Dhanachandra Singh, Annette Bellar, Avinash Kumar, Lars N. Deutz, et al. “Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB.” Proceedings of the National Academy of Sciences of the United States of America 121, no. 31 (July 2024): e2314760121. https://doi.org/10.1073/pnas.2314760121.

Covert, Lauren T., Hailee Patel, Alaa Osman, Lavonia Duncan, Jeffrey Dvergsten, and George A. Truskey. “Effect of type I interferon on engineered pediatric skeletal muscle: a promising model for juvenile dermatomyositis.” Rheumatology (Oxford) 63, no. 1 (January 4, 2024): 209–17. https://doi.org/10.1093/rheumatology/kead186.

Shores, Kevin L., and George A. Truskey. “Mechanotransduction of the vasculature in Hutchinson-Gilford Progeria Syndrome.” Frontiers in Physiology 15 (January 2024): 1464678. https://doi.org/10.3389/fphys.2024.1464678.

2023

Lee, Jounghyun H., Kevin L. Shores, Jason J. Breithaupt, Caleb S. Lee, Daniella M. Fodera, Jennifer B. Kwon, Adarsh R. Ettyreddy, et al. “PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system.” APL Bioengineering 7, no. 4 (December 2023): 046103. https://doi.org/10.1063/5.0167440.

Truskey, George A. “The Potential of Deep Learning to Advance Clinical Applications of Computational Biomechanics.” Bioengineering (Basel, Switzerland) 10, no. 9 (September 2023): 1066. https://doi.org/10.3390/bioengineering10091066.

Zhang, Qiao, Ren-Zhi Zhan, Marisa Patsy, Binjie Li, Yifan Chen, Barbara D. Lipes, Nenad Bursac, and George A. Truskey. “Differential Response of Engineered Human Cardiac Tissues to Delta and Omicron COVID-19 Virus.” J Am Heart Assoc 12, no. 12 (June 20, 2023): e029390. https://doi.org/10.1161/JAHA.123.029390.

Abutaleb, Nadia O., Leigh Atchison, Leandro Choi, Akhil Bedapudi, Kevin Shores, Yantenew Gete, Kan Cao, and George A. Truskey. “Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome.” Scientific Reports 13, no. 1 (March 2023): 5032. https://doi.org/10.1038/s41598-023-32035-3.

Covert, Lauren T., Hailee Patel, Alaa Osman, Jeffrey Dvergsten, and George A. Truskey. “EFFECT OF TYPE I INTERFERON ON ENGINEERED HUMAN SKELETAL MUSCLE: A PROMISING MODEL FOR JUVENILE DERMATOMYOSITIS.” In CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 41:414–15, 2023.

2022

Torres, Maria J., Xu Zhang, Dorothy H. Slentz, Timothy R. Koves, Hailee Patel, George A. Truskey, and Deborah M. Muoio. “Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities.” IScience 25, no. 10 (October 21, 2022): 105189. https://doi.org/10.1016/j.isci.2022.105189.

Bishawi, Muath, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, et al. “Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.” IScience 25, no. 4 (April 15, 2022): 104086. https://doi.org/10.1016/j.isci.2022.104086.

Aydin, Onur, Austin P. Passaro, Ritu Raman, Samantha E. Spellicy, Robert P. Weinberg, Roger D. Kamm, Matthew Sample, et al. “Principles for the design of multicellular engineered living systems.” APL Bioengineering 6, no. 1 (March 2022): 010903. https://doi.org/10.1063/5.0076635.

Oliver, Catherine E., Hailee Patel, James Hong, Jonathan Carter, William E. Kraus, Kim M. Huffman, and George A. Truskey. “Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells.” J Tissue Eng Regen Med 16, no. 2 (February 2022): 128–39. https://doi.org/10.1002/term.3266.

Bishawi, M., M. Kaplan, S. Chidyagwai, J. Cappiello, A. Cherry, D. MacLeod, K. Gall, et al. “Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 13352 LNCS:137–49, 2022. https://doi.org/10.1007/978-3-031-08757-8_13.

Zhang, Xu, Nadia O. Abutaleb, Ellen Salmon, and George A. Truskey. “In Situ Fabrication and Perfusion of Tissue-Engineered Blood Vessel Microphysiological System.” Methods in Molecular Biology (Clifton, N.J.) 2375 (January 2022): 77–90. https://doi.org/10.1007/978-1-0716-1708-3_7.

Truskey, George, Ellery Jones, Svati Shah, and Robert McGarrah. “ASSESSING THE ROLE OF BRANCHED CHAIN AMINO ACIDS IN ATHEROSCLEROSIS USING A HUMAN VASCULAR MICROPHYSIOLOGICAL SYSTEM.” In TISSUE ENGINEERING PART A, 28:S570–S570, 2022.

Truskey, George, and Anandita Ananthakumar. “MODELING SKELETAL MUSCLE FIBROSIS USING A HUMAN MICROPHYSIOLOGICAL SYSTEM.” In TISSUE ENGINEERING PART A, 28:S570–71, 2022.

Vann, Christopher G., Xin Zhang, Alastair Khodabukus, Melissa C. Orenduff, Yu-Hsiu Chen, David L. Corcoran, George A. Truskey, Nenad Bursac, and Virginia B. Kraus. “Differential microRNA profiles of intramuscular and secreted extracellular vesicles in human tissue-engineered muscle.” Front Physiol 13 (2022): 937899. https://doi.org/10.3389/fphys.2022.937899.

2021

Abutaleb, Nadia O., and George A. Truskey. “Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress.” STAR Protocols 2, no. 2 (June 2021): 100394. https://doi.org/10.1016/j.xpro.2021.100394.

Zhang, Qiao, Èlia Bosch-Rué, Román A. Pérez, and George A. Truskey. “Biofabrication of tissue engineering vascular systems.” APL Bioengineering 5, no. 2 (June 2021): 021507. https://doi.org/10.1063/5.0039628.

Saha, Krishanu, Erik J. Sontheimer, P. J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu, Stephen A. Murray, et al. “The NIH Somatic Cell Genome Editing program.” Nature 592, no. 7853 (April 2021): 195–204. https://doi.org/10.1038/s41586-021-03191-1.