Publications

2024

Lopez, Isabella, and George A. Truskey. “Multi-cellular engineered living systems to assess reproductive toxicology.” Reproductive Toxicology (Elmsford, N.Y.) 127 (May 2024): 108609. https://doi.org/10.1016/j.reprotox.2024.108609.

Covert, Lauren T., Hailee Patel, Alaa Osman, Lavonia Duncan, Jeffrey Dvergsten, and George A. Truskey. “Effect of type I interferon on engineered pediatric skeletal muscle: a promising model for juvenile dermatomyositis.” Rheumatology (Oxford) 63, no. 1 (January 4, 2024): 209–17. https://doi.org/10.1093/rheumatology/kead186.

2023

Lee, Jounghyun H., Kevin L. Shores, Jason J. Breithaupt, Caleb S. Lee, Daniella M. Fodera, Jennifer B. Kwon, Adarsh R. Ettyreddy, et al. “PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system.” APL Bioengineering 7, no. 4 (December 2023): 046103. https://doi.org/10.1063/5.0167440.

Truskey, George A. “The Potential of Deep Learning to Advance Clinical Applications of Computational Biomechanics.” Bioengineering (Basel, Switzerland) 10, no. 9 (September 2023): 1066. https://doi.org/10.3390/bioengineering10091066.

Zhang, Qiao, Ren-Zhi Zhan, Marisa Patsy, Binjie Li, Yifan Chen, Barbara D. Lipes, Nenad Bursac, and George A. Truskey. “Differential Response of Engineered Human Cardiac Tissues to Delta and Omicron COVID-19 Virus.” J Am Heart Assoc 12, no. 12 (June 20, 2023): e029390. https://doi.org/10.1161/JAHA.123.029390.

Abutaleb, Nadia O., Leigh Atchison, Leandro Choi, Akhil Bedapudi, Kevin Shores, Yantenew Gete, Kan Cao, and George A. Truskey. “Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome.” Scientific Reports 13, no. 1 (March 2023): 5032. https://doi.org/10.1038/s41598-023-32035-3.

Covert, Lauren T., Hailee Patel, Alaa Osman, Jeffrey Dvergsten, and George A. Truskey. “EFFECT OF TYPE I INTERFERON ON ENGINEERED HUMAN SKELETAL MUSCLE: A PROMISING MODEL FOR JUVENILE DERMATOMYOSITIS.” In CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 41:414–15, 2023.

2022

Torres, Maria J., Xu Zhang, Dorothy H. Slentz, Timothy R. Koves, Hailee Patel, George A. Truskey, and Deborah M. Muoio. “Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities.” IScience 25, no. 10 (October 21, 2022): 105189. https://doi.org/10.1016/j.isci.2022.105189.

Bishawi, Muath, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, et al. “Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.” IScience 25, no. 4 (April 15, 2022): 104086. https://doi.org/10.1016/j.isci.2022.104086.

Aydin, Onur, Austin P. Passaro, Ritu Raman, Samantha E. Spellicy, Robert P. Weinberg, Roger D. Kamm, Matthew Sample, et al. “Principles for the design of multicellular engineered living systems.” APL Bioengineering 6, no. 1 (March 2022): 010903. https://doi.org/10.1063/5.0076635.

Oliver, Catherine E., Hailee Patel, James Hong, Jonathan Carter, William E. Kraus, Kim M. Huffman, and George A. Truskey. “Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells.” J Tissue Eng Regen Med 16, no. 2 (February 2022): 128–39. https://doi.org/10.1002/term.3266.

Zhang, Xu, Nadia O. Abutaleb, Ellen Salmon, and George A. Truskey. “In Situ Fabrication and Perfusion of Tissue-Engineered Blood Vessel Microphysiological System.” Methods in Molecular Biology (Clifton, N.J.) 2375 (January 2022): 77–90. https://doi.org/10.1007/978-1-0716-1708-3_7.

Truskey, George, Ellery Jones, Svati Shah, and Robert McGarrah. “ASSESSING THE ROLE OF BRANCHED CHAIN AMINO ACIDS IN ATHEROSCLEROSIS USING A HUMAN VASCULAR MICROPHYSIOLOGICAL SYSTEM.” In TISSUE ENGINEERING PART A, 28:S570–S570, 2022.

Truskey, George, and Anandita Ananthakumar. “MODELING SKELETAL MUSCLE FIBROSIS USING A HUMAN MICROPHYSIOLOGICAL SYSTEM.” In TISSUE ENGINEERING PART A, 28:S570–71, 2022.

Vann, Christopher G., Xin Zhang, Alastair Khodabukus, Melissa C. Orenduff, Yu-Hsiu Chen, David L. Corcoran, George A. Truskey, Nenad Bursac, and Virginia B. Kraus. “Differential microRNA profiles of intramuscular and secreted extracellular vesicles in human tissue-engineered muscle.” Front Physiol 13 (2022): 937899. https://doi.org/10.3389/fphys.2022.937899.

Bishawi, M., M. Kaplan, S. Chidyagwai, J. Cappiello, A. Cherry, D. MacLeod, K. Gall, et al. “Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 13352 LNCS:137–49, 2022. https://doi.org/10.1007/978-3-031-08757-8_13.

2021

Abutaleb, Nadia O., and George A. Truskey. “Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress.” STAR Protocols 2, no. 2 (June 2021): 100394. https://doi.org/10.1016/j.xpro.2021.100394.

Zhang, Qiao, Èlia Bosch-Rué, Román A. Pérez, and George A. Truskey. “Biofabrication of tissue engineering vascular systems.” APL Bioengineering 5, no. 2 (June 2021): 021507. https://doi.org/10.1063/5.0039628.

Saha, Krishanu, Erik J. Sontheimer, P. J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu, Stephen A. Murray, et al. “The NIH Somatic Cell Genome Editing program.” Nature 592, no. 7853 (April 2021): 195–204. https://doi.org/10.1038/s41586-021-03191-1.

Lee, Jounghyun H., Zaozao Chen, Siyu He, JoyceK Zhou, Alexander Tsai, GeorgeA Truskey, and Kam W. Leong. “Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels.” Advanced Biology 5, no. 4 (April 2021): e2000428. https://doi.org/10.1002/adbi.202000428.

Kennedy, Crystal C., Erin E. Brown, Nadia O. Abutaleb, and George A. Truskey. “Development and Application of Endothelial Cells Derived From Pluripotent Stem Cells in Microphysiological Systems Models.” Frontiers in Cardiovascular Medicine 8 (January 2021): 625016. https://doi.org/10.3389/fcvm.2021.625016.

2020

Kondash, Megan E., Anandita Ananthakumar, Alastair Khodabukus, Nenad Bursac, and George A. Truskey. “Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle.” Tissue Engineering and Regenerative Medicine 17, no. 6 (December 2020): 801–13. https://doi.org/10.1007/s13770-020-00242-y.

Zhang, Xu, Muath Bishawi, Ge Zhang, Varun Prasad, Ellen Salmon, Jason J. Breithaupt, Qiao Zhang, and George A. Truskey. “Modeling early stage atherosclerosis in a primary human vascular microphysiological system.” Nature Communications 11, no. 1 (October 2020): 5426. https://doi.org/10.1038/s41467-020-19197-8.

Sklivas, Alexander Byron, Dante Goss, Nenad Bursac, Alastair Khodahukus, Tim Koves, Deborah Muoio, Lauran Madden, George A. Truskey, William E. Kraus, and Monica J. Hubal. “Gene Expression Differences In Three-dimensional Myobundles Compared To Two-dimensional Myocultures.” Medicine & Science in Sports & Exercise 52, no. 7S (July 2020): 781–82. https://doi.org/10.1249/01.mss.0000683732.61182.4f.

Salmon, Ellen E., Jason J. Breithaupt, and George A. Truskey. “Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.” Cells 9, no. 5 (May 2020): E1292. https://doi.org/10.3390/cells9051292.