|Title||A novel in situ monitoring system of 3D engineered muscle|
|Publication Type||Conference Paper|
|Year of Publication||2020|
|Authors||X Zhang, and GA Truskey|
|Conference Name||21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017|
In this work, we developed an in situ force monitoring system of skeletal muscle based on “ecoflex-coupling method”. The three dimensional (3D) human skeletal muscle myobundles was fabricated in series with ecoflex (platinum-catalyzed silicones) film containing microbeads. Through mapping the displacement of the microbeads in ecoflex, a linear relation between muscle contractile force production and ecoflex film stretch was established. Then the force production of engineered muscle was real-time monitored in situ.