| Title | A novel in situ monitoring system of 3D engineered muscle |
| Publication Type | Conference Paper |
| Year of Publication | 2020 |
| Authors | X Zhang, and GA Truskey |
| Conference Name | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
| Date Published | 01/2020 |
| Abstract | In this work, we developed an in situ force monitoring system of skeletal muscle based on “ecoflex-coupling method”. The three dimensional (3D) human skeletal muscle myobundles was fabricated in series with ecoflex (platinum-catalyzed silicones) film containing microbeads. Through mapping the displacement of the microbeads in ecoflex, a linear relation between muscle contractile force production and ecoflex film stretch was established. Then the force production of engineered muscle was real-time monitored in situ. |