Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts.

TitleHuman iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts.
Publication TypeJournal Article
Year of Publication2020
AuthorsNO Abutaleb, and GA Truskey
JournalCell stem cell
Volume26
Issue2
Start Page136
Pagination136 - 137
Date Published02/2020
Abstract

Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.

DOI10.1016/j.stem.2020.01.011
Short TitleCell stem cell