Relationship between LDL residence time and macrophage accumulation in the rabbit aorta

TitleRelationship between LDL residence time and macrophage accumulation in the rabbit aorta
Publication TypeJournal Article
Year of Publication2001
AuthorsTruskey, GA, Li, H, Kait, J, and Irick, J
JournalAmerican Society of Mechanical Engineerings, Bioengineering Division (Publication) BED
Volume50
Start Page679
Pagination679 - 680
Date Published01/2001
Abstract

The relationship between low density lipoprotein (LDL) residence time and macrophage accumulation in the rabbit aorta was studied. It was hypothesized that longer LDL residence times increased the likelihood for modification of LDL. It was found that for rabbits fed on a hypercholesterolemic diet, elevations in macrophage densities were associated with higher concentrations and longer residence times of 125I-LDL.

Short TitleAmerican Society of Mechanical Engineerings, Bioengineering Division (Publication) BED