Diffusion properties of capsular tissue

TitleDiffusion properties of capsular tissue
Publication TypeJournal Article
Year of Publication1996
AuthorsSharkawy, AA, Klitzman, B, Truskey, GA, and Reichert, WM
JournalTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Volume2
Start Page132-
Pagination132- -
Date Published01/1996
Abstract

The effect of capsule formation around a subcutaneous implant is discussed. Polyvinyl alcohol sponge and stainless steel wire mesh materials were implanted. The results show that the diffusion coefficients of fluorescein through capsular tissue are approximately 25% lower than those through the subcutaneous tissue. The tissue which encapsulates subcutaneously implanted sensors will retard the diffusion of low molecular weight analytes diffusing from the microvasculature and the extent of diffusion depends on the thickness and vascularity of the capsule.

Short TitleTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium